ThatJuanMexican
117736
7315
33
Sep 2, 2020 7:37 PM
ThatJuanMexican
117736
7315
33
floofnmeeps
Little bitch receptor better recognize
HumanCats
My face is a cocks inhibitor.
orbitn
"all inflammatory pain is gone" I laugh, as i weep because im about to experience another night of tossing/turning pain because my dumb ass>
orbitn
thought it would be a BRILLIANT idea to take a tolerance break of my stronger meds rather than go up a small dose increment. Fuck my spine>
orbitn
and it's "trying to turn into one long bone" thing. AS, you unpronounceable bitch.
247Lurker
TheFingerGunsGuy
B1GB3RN
Jamie Hyneman looking as dapper as ever.
Zephrman
I always wondered what he's doing these days.. now I know
penut61
Cox Bloxer
Turbolibros
Cox antagonist?
Ghostman0
Nothing like that oxy though
ThorsCatOdin
Like a good lil' bitch should. altho, & unfortunately, it tends to block both pathways - pro AND anti-inflammatory - fish oils seem a wiser
berlinson
Ibuprofen is the best hangover medicine
copingcabana
It's like a thermos. It keeps hot things hot and cold things cold. But how does it know?
barnwolf
So if you don't have pain from inflamation, it does nothing?
Zyrgon
That would make sense
VagrantDust
Now ask how Acetaminophen works!
BillandTedsUnremarkableTripToCostCo
Not as well.
freegallegal
Can you dumb that down for me?
pazooPositivityPlayer
Unfortunately ibuprofen know exactly how to target my IBS
Snickker
I’m allergic to nsaids so I get you.
littlebadwolf1990
Colitis here....I feel your pain friend
Kwalaberg
Really? I have Crohn’s and it helps me.
littlebadwolf1990
Ibuprofen is well known to trigger flares. But like everything with IBD, for some people it's fine and others it's not
periwinklepanda
Colitis here too. And unfortunately it's the only thing that sort of takes the edge off menstrual cramps.
littlebadwolf1990
I had to switch to co-codamol for this. Paracetamol does absolutely nothing lol
traumapatient
I like how its correct and dumbed down, but still respectful to the requestor. Marvellous :) +1
in70x
Ibuprofen works on all body parts at once.
kingcrabrangoon
Kulten for President!
dudedude09
A cox inhibitor? Isn’t that what allows time travel?
HeckSpawn
It's Motrin® that you have to tell where it hurts. It doesn't know till it's told...
f0622
But isn't inflammation necessary to provide nutrients to repare cells and/or fight foreign bodies (virus, bacteria, ...)?
SithElephant
It can be needed, but in some cases it is not a helpful response and the body goes overboard.
mxfemme
I'm over here with a broken ass (Coccyx) thanks for the informative chuckle.
SephiRothIRA
That’s cool. So is hydrocodone which, iirc, tells the brain “there is no pain”
amundost
It's almost as effective as sex to remove pains...
justmemyselfi
I’ve found that just the prospect of sex can make the pain lessen, at least until orgasm
KawaiiTwat
After orgasm you're just as fucked again. At Least for women, can't speak for men here.
ricerescue
It's much faster acting tho, so you take your pills, and have sex while you wait for it to take effect.
justmemyselfi
Same
Dpunch4
I mean if they have a high refractory period, yes, you're fucked again.
Chakra5
this dude dumbs well
DaveSamsonite
Excedrin works cuz it allows higher blood flow to the brain. Simple enough?
MedicallyAccurateReplies
Another powerful cox inhibitor is your Mum's fat ass. (Obviously not a medically accurate reply).
AlaSnackbar
Wrong. not a inhibitor. An activator. https://en.m.wikipedia.org/wiki/Enzyme_activator
2ndplaceisasetofsteakknives
No it's medically accurate.
YoSamiteSam
If you're a MILF, I wanna see your fat ass.
FlyingButtPliers
theimgurappsucksballs
Hungrypiemonger
Hes such a showman
swolentoast
Scrolled down for the cox inhibitor jokes. Not disappointed.
Eldibs
Yeah, you would scroll down for the cox.
greatgooglymooglytheoneandonly
oilgod
Works the other way around, cox put that ass to sleep. To paraphrase Ice Cube...
MrJackedBroccoli
I alwayas found her to be more of a cox receptor. Non medical opinion of course
itrynottocommentbutyoumakemecringe
Dumb it down for me.
C4melC4se
Thank u for ur service
Iamnotacreativeman
No no , as a porn medical professional, that's actually accurate
forgetthisnoise
Fucking cracked me up man
KrakedUp
Seems to exacerbate the inflammation in specific regions
Hammertulski
Another fun cox trivia is the Cox's Orange Pippin apple rattles when you shake it. It doesn't all have to be dirty, goodness ya'll.
EricPisch
It didn’t stop my cox last night when I crawled off her
ZougasNewFist
*rolled off her like a bouncy castle
MyNameIsJesusAndIStealHubcapsFromCars
this is when the fun begins!
TheDaharMaster
Now THIS is shitposting.
blakeatwork
*slithered off her like a slip n' slide
DachshundKing
Tumbled down her like an oily goat off a mountain.
ZougasNewFist
Why the oil? It's unnecessary if tumbling not sliding, and the mountain is likely so gritty it would be rendered ineffective anyway
blakeatwork
Yea nah, you win that one :D
Alfa799
So, it's a cox blocker.
Onlyamusingtomyself
I think technically a blocker would bind to the receptor and not the enzyme
dragonflyy69
PopeyeTheSailor
Wouldnt it be easier to have Cox Cable?
ughhhAsif
Right. It blox cox.
explainer
You don't like cox?
3654798521
Don't even get started about the Generation 1 and 2 Cox blockers!
koops
Mum, daughter combo?
tooomanystevesgotbanned
Fun fact: Nurofen got sued by the Oz government over their "Nurofen targets pain" adverts.
tiramigiu
nurofen also got into trouble in britain for selling the same drug in lots of different packagings, suggesting it was for different pains.
tiramigiu
https://www.telegraph.co.uk/news/health/12049845/Do-you-find-this-Nurofen-packaging-misleading.html
DefinitelyNotMadeOfBees
Wow, I didn't know Oz is still around; I thought after the Wizard was overthrown it devolved into a series of small nation states.
tooomanystevesgotbanned
https://www.abc.net.au/news/2016-12-16/nurofen-fined-6m-for-misleading-consumer/8126450
monocline
Dumb it down just a hair more?
HannaHPirhannaH
Ibuprofen is scent dog, scent dog found bad guy. Doggy said heckin no, bad guy listened .
theskbt
Pill goes 1v1 me, wins.
LuminousExpanse
HAADDARAHHHAH...AhhurruHAHAHAHDAAARR
Navrodel
It doesn't actually know, it tells everything to stop responding to excess pain, and only matters on the part that's a problem.
caldella
Ibuprofin doesn't target a specific place - it stops your cells from producing hurt maker. You feel that change the most where it's hurting.
wellthisjustgotinteresting
It targets all pain, anywhere in your body.
theskbt
Pull goes 1v1 me, wins.
FiftyShadesOfMascarpone
Inflammation is triggered by messenger proteins. These can be produced by damaged cells or by white blood cells that detect an infection. …
FiftyShadesOfMascarpone
Sometimes the immune system goes haywire and produces these proteins for no discernible reason, causing autoinflammatory disease. Ibuprofen…
FiftyShadesOfMascarpone
is absorbed from the digestive tract into the bloodstream. If it happens upon these messenger proteins, it binds to them and thus alters ...
FiftyShadesOfMascarpone
their chemical structure and renders them useless. This stops the inflammatory response that causes the pain.
LongtimeLurkerFirsTimePoster
Ibuprofin knows what body part hurts.
pharmie01
No. We need to stop dumbing down things. You get a hair smarter, sir (or madam). /s
EvanStageTech
' |' ' |' - | `
JustGoWithIt
Pain is hangry, ibuprofen is snickers.
definitelynotaseagull
Cells by like: 'ow' Ibuprofen be like: 'daddy chill'
Shpadoinkleman
Brain gets "this hurts" messenger from hurt part. Ibuprofin goes to brain's front door and powerbombs messenger before it gets inside.
eadanke
ibuprofen doesn't talk to the pain, it talks to the pain's manager.
missastromccluskey
Thanks!
ebonybutterfree
My favorite explanation so far.
antman2988
Ibuprofen tell thing that produces ouch ouch not to produce ouch ouch
Ratnavati
Magic
swolentoast
Pill antagonizes cox. Cox goes flaccid. No more pain.
NeverDunNuffin
UsernameMayBeSubjectToChange
Hahaha, +1 for appropriate GIF
CottonTShirtz
Cells in distress produce the cox thing, aspirin and NSAIDs either deactivate the cox or bind to the pain receptor in its place.
CottonTShirtz
A cox blocker if you will.
Bollockstousernames
Underrated punchline +1
theskbt
Pill goes 1v1 me, wins.
electricsillygoose
OUCH + IBUPROFEN = MAGIC OUCH GONE
MikeMcAwesome91
Jfc now I gotta do math?
PJVeddersGirl
IllusivePanda
Osmosis Jones is a documentary and the medicine knows exactly where to go.
CaptSchmidtGaming
the simpsons ruined us all
capngoat
https://youtu.be/Anmhf2ZvquY
capngoat
I know it's Futurama and not Simpsons and I know they're talking about alcohol making you stupid but this scene came to my mind first.
WilliamKeith
Pain happens because some of your nerves fire up molecular machines to release particular chemicals. Anywhere it finds those machines it
WilliamKeith
is attracted to them like a magnet and interferes. It "knows where pain is" because pain machines are the only spots it does anything.
Kil0g
“Hey pain receptor....” *punches pain receptors in face* ibuprofen...probably.
watisdisidonteven
Brain make liquid that make you go ouch, pill tell brain no do that. Brain like "okay."
[deleted]
[deleted]
CaptSchmidtGaming
In english?
PolarHailStorm
This pain is drivin' daown the wrong side 'o th' road naow innit
capngoat
Ibuprofen has nanochips, which are controlled by Bill Gates to target the areas that hurt. Also something about 5g I think?
TheNextHafthorBjornsson
Did someone say 5g? Everyone get your shungite!
CaptSchmidtGaming
fucking perfect. i can't believe someone was able to make even dumber. (slow clap)
theshinobi23
They're close, but wrong. It's a mind control pill that also makes your brain think there's no pain.
Ryebread91
Wubbalubbadubdubb101
But that's in American English though.
LordNergal
That's because, unlike the British, Americans don't come pre-dumbed.
Sumciak
What about paracetamol????
GetSmartBeEvil
Protein creates ouchy molecule. Ibuprofen slaps that protein in the face. No more ouchy molecule made.
sarabear
Prostaglandins is a PITA to type. From now on, I’m using ‘ouchy molecule’
neonbananarat
Lmao!!
stuminthrowaway
How about acetaminophen? What does that do that's similar/different and how do I know which to take for what purposes?
MechanizedAttackPidgeon
Similar but ibuprofen and aspirin deal with inflimation better (NSAID) and Tylenol better for general pain relief and fevers, i think?
SithElephant
/me is continually irritated that ACAP is not coformulated with NAC.
Rivalyn
Acetaminophen works by basically magic. It stops pain, somehow, but nobody is really sure how.
EverydayIsLegDayBecauseImRunningFromMyProblems
Ive heard that we truly dont know how it works. Its crazy how much we still have to learn and r taking this stuff without understanding it.
Rivalyn
It's also kinda dangerous; acetaminophen poisoning causes severe liver damage. I know this first hand, for reasons.
EverydayIsLegDayBecauseImRunningFromMyProblems
Dang, with ace I always drink plenty of water because of this known risk. Its unfortunate it happened to you and I hope people drink.
Zyrgon
I take it with NAC supplement which I believe neutralises the negative effects. Ibuprofen however, I never take as it ravages the stomach.