Gene editing in the lungs

Apr 2, 2023 5:36 PM

TamilTechNews

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https://www.youtube.com/watch?v=N1G_RgjJvKo
https://news.mit.edu/2023/new-nanoparticles-can-perform-gene-editing-lungs-0330

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lungs

crispr

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Considering how quickly we are polluting our air - we should really ramp up production on these bad boys

3 years ago | Likes 28 Dislikes 0

Look ma, new bio weapon vector!

3 years ago | Likes 10 Dislikes 3

...Or as a airborne weapon...

3 years ago | Likes 1 Dislikes 4

Lifelong asthmatic with chronic bronchitis here. Sign me the fuck up.

3 years ago | Likes 1 Dislikes 0

Ok, but will it let me have 5G?

3 years ago | Likes 1 Dislikes 0

Yeah but it’s the Kochs so fuck ‘em

3 years ago | Likes 7 Dislikes 2

the koch institute is just the cancer biology department at MIT - its named that because he gave them enough money to get it named that 16 years ago. the kochs had nothing to do with this research. you are just doing “soros-backed DA”

3 years ago | Likes 1 Dislikes 0

B-B-but it will save lives potentially

3 years ago | Likes 2 Dislikes 0

No that's not "gene editing". Just like the COVID vaccine doesn't edit your genes. It'd tell your cells to make a protein. Easier than forcing a protein from the outside into the cells (I assume).

3 years ago | Likes 2 Dislikes 2

The claim is that the treatment will use mrna to instruct the cells to produce crispr proteins and edit themselves.

3 years ago | Likes 2 Dislikes 0

Awesome then we can start using asbestos again. :P

3 years ago | Likes 1 Dislikes 0

I don't believe this for a second, but I can't wait for this sciency magic to fuck up may asthma

3 years ago | Likes 1 Dislikes 1

Can't wait to not be able to afford that treatment

3 years ago | Likes 1 Dislikes 1

This is how we get zombies/grey goo.

3 years ago | Likes 1 Dislikes 3

How does this not cause the body to reject the lungs as "foreign", similar to how transplants can go south?

3 years ago | Likes 3 Dislikes 0

"The new particles also break down quickly, allowing them to be cleared from the lung within a few days and reducing the risk of inflammation. The particles could also be delivered multiple times to the same patient if repeat doses are needed. This gives them an advantage over another approach to delivering mRNA, which uses a modified version of harmless adenoviruses which are very effective at delivering RNA but can’t be given repeatedly because they induce an immune response in the host."

3 years ago | Likes 2 Dislikes 0

Not sure if this is exactly the same thing, but it seemed relevant to your question.

3 years ago | Likes 2 Dislikes 0

Not that any of us in America would be able to afford it.

3 years ago | Likes 1 Dislikes 1

This makes conservatives angry, for some reason.

3 years ago | Likes 1 Dislikes 0

WOO HOO. LIGHT 'EM IF YOU GOT 'EM!!!!! - People I know.

3 years ago | Likes 1 Dislikes 0

3 years ago | Likes 58 Dislikes 2

v

3 years ago | Likes 7 Dislikes 0

NANOMACHINES, SON!

3 years ago | Likes 20 Dislikes 0

What's this from?

3 years ago | Likes 1 Dislikes 0

Literally said this when I saw the title and description lol

3 years ago | Likes 4 Dislikes 0

I wonder if someone can also use this research to help out chronic acute asthma sufferers

3 years ago | Likes 3 Dislikes 0

Isn’t this the start of what actually happened in the Marvel Universe where they used nanobots to control the villains?

3 years ago | Likes 1 Dislikes 0

Can... Can it clear out asbestos exposure? Asking for people who were hired as teens to help clean up wreckage by absolute idiots who wanted to save a buck by not getting actual licensed disposal crews

3 years ago | Likes 12 Dislikes 0

Unfortunately, I don't think gene-editing can remove the scarring that is the cause of asbestosis. It's not a viral malady, but damage accrued by prolonged exposure to the fibers causing persistent injury that scars over until the accumulation of scar tissue makes it more and more difficult to breathe. If they could find a way to replace scar tissue with healthier tissue, then it might be something that can be fixed.

3 years ago | Likes 5 Dislikes 0

Yeah....I worked in heavy factories for 35 years....all manner of chemicals in the air, bad conditions....we just accepted it....the pay was great....now, I have so much scarring.... 3000 mgs of immunosuppressant daily.....hey...it was a good ride.

3 years ago | Likes 5 Dislikes 0

World militaries: Can we have toxic gas immunity?

3 years ago | Likes 1 Dislikes 0

Not in... one of the midwest red states. I honestly can't keep up with which one is banning what.

3 years ago | Likes 1 Dislikes 0

From the Koch Institute? Will it also make you vote in favor of the oligarchy?

3 years ago | Likes 3 Dislikes 1

"Finally" *opens a pack of cigarettes

3 years ago | Likes 1 Dislikes 0

Looks like I am back on those clove cigarettes.

3 years ago | Likes 1 Dislikes 0

I wonder if we'll ever come up with something for COPD.

3 years ago | Likes 1 Dislikes 0

Don't worry: The anti-GMO people will ensure it never happens.

3 years ago | Likes 3 Dislikes 1

OOh I wonder if it will help people living with lung cancer

3 years ago | Likes 1 Dislikes 0

If this comes to fruition, we’ll all breathe a bit easier

3 years ago | Likes 458 Dislikes 2

Whio is this we? Americans aren't getting shit.

3 years ago | Likes 1 Dislikes 0

well except for anyone who has a conspiracy against mRna vax’s

3 years ago | Likes 16 Dislikes 0

As some who's got COPD at 36, I fuckin hope so

3 years ago | Likes 5 Dislikes 0

And my long COVID says thanks.

3 years ago | Likes 2 Dislikes 0

Don't worry: The anti-GMO people will ensure it never happens.

3 years ago | Likes 2 Dislikes 1

There were real ecological concerns when gene editing started. Like everything, the better we understand it, the more responsibly we can use it.

3 years ago | Likes 2 Dislikes 0

the opponents never let not understanding anything get in the way of opposing it

3 years ago | Likes 1 Dislikes 0

3 years ago | Likes 1 Dislikes 0

This news is a breath of fresh air, for sure.

3 years ago | Likes 1 Dislikes 0

We all?? Hahahahahha! You better be rich.

3 years ago | Likes 1 Dislikes 0

*sigh*

3 years ago | Likes 1 Dislikes 0

I think anti vaxxers should be banned from this bc it’s RNA based

3 years ago | Likes 1 Dislikes 0

Good news, terrifying news for possible weapons research.

3 years ago | Likes 16 Dislikes 4

There’s a Fridge episode that ran a similar concept.

3 years ago | Likes 3 Dislikes 0

what advantages as a weapon would this have over something like chlorine gas

3 years ago | Likes 7 Dislikes 2

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3 years ago (deleted Apr 3, 2023 4:20 AM) | Likes 0 Dislikes 0

CRISPR is not contagious so why is it a benefit to make enemy soldiers sick later instead of immediately? and there are chemical toxins that already work like that

3 years ago | Likes 2 Dislikes 1

Yeah, when it comes to chemical or biological weapons we already have access to extremely effective ones that are much easier and cheaper to produce

3 years ago | Likes 2 Dislikes 1

The important word is "discerning." A lot of chemical/biological agents affect both sides equally, that's part of the practical reason they aren't used in warfare. If you can edit the DNA of your soldiers with a big red flag for this thing, then this particle is just going to kill your enemies, and leave your troops completely alone

3 years ago | Likes 2 Dislikes 1

You can tag your soldiers with a specific marker, a "do not touch" marker. And then basically shell your own troops with this nanoparticle with no fear. A discerning chemical warfare agent is the thing of nightmares my dude

3 years ago | Likes 3 Dislikes 2

you… can’t? this is just a delivery method for CRISPR, and even then its administered intratracheally.

3 years ago | Likes 4 Dislikes 0

Slightly less horrifyingly, if you manage to make this kind of thing shelf stable, you can use it in a similar method as paint bombs or ink packs, where you can trigger a specific genetic trait in people exposed to it. Like nasty breath if you broke into a safe, as an unrealistic example. Easily find rebels, terrorists, and bank robbers

3 years ago | Likes 2 Dislikes 1

I'm not saying we shouldn't research this, CRISPR technology is amazing. I'm just pointing out some of the scary things that are riding its coattails

3 years ago | Likes 2 Dislikes 1

that is not how either CRISPR or genetic variation in humans works, and it would be orders of magnitudes easier to do what you describe with just chemical toxins

3 years ago | Likes 2 Dislikes 1

Genocide? Reverse engineering tech like this to target particular genes present in certain ethnicities? The only challenge would be vector, not someting that would take a long time to research. Utilizing tech like this is not for battlefield use, its for use on civilian populations, oftentimes unsuspecting.

3 years ago | Likes 7 Dislikes 13

thats science fiction - theres no single unique genetic site that would work for something like that. and also why would they do that when they could just gather up ethnic minorities using guys with guns and then shoot them

3 years ago | Likes 13 Dislikes 3

Less culpability for governments involved, and its quite clear you have a nagging desire to be contrarian. So we're done here.

3 years ago | Likes 4 Dislikes 14

no i actually understand genetics and i am telling you that you dont and are baselessly fearmongering

3 years ago | Likes 10 Dislikes 2