Two Metabolic Origins of Life - New Study

Aug 8, 2026 1:05 AM

Oktay74tn

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Two Metabolic Origins of Life - New Study
Oktay Yürük aka Oktay74tn, science and tech content
https://imgur.com/user/Oktay74tn

This is the Beebe Vent Field near the Cayman Islands, the deepest known hydrothermal vent site in the world, 5 kilometers (3.1 miles) below sea level. It is a candidate for the origin of life. According to a new scientific study, there could be two metabolic origins of life.

The phylogenetic tree of life describes the relationships between organisms. The three main groups are the domains: Bacteria, Archaea and Eukarya. LUCA, the last universal common ancestor, is the hypothetical latest common ancestral population of all single-celled organisms.

This is the distribution of ribosomal and core metabolism protein families across bacterial classes shown in blue and archaeal orders in red (LBCA and LACA are the last common ancestors of bacteria and archaea). The enzymes that catalyze the reactions are not conserved across the evolutionary divide that separates bacteria and archaea. The two lineages made the transition to the free-living state independently.

In this diagram, inorganic substrates are shown at the left. A network of about 400 reactions converts these compounds into amino acids and nucleobases, represented by one-letter codes, and cofactors. This network evolved over time. The pink and red nodes represent reactions catalyzed by transition metals.

Adenosine triphosphate ATP is the energy molecule in living cells. An average human recycles 50 kilograms of ATP per day. Adenosine diphosphate ADP is the product of a palladium-catalyzed phosphorylation with phosphite. Proto-cells developed more and more enzymes over time until they became independent of metals.

At the end of the process, free-living bacteria and archea emerged. Hot springs such as the Grand Prismatic Spring of the Yellowstone National Park are home to the robust archea.
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Intermediate stages in the origin of metabolism at a phosphorylating hydrothermal vent
Natalia Mrnjavac, Nadja K. Hoffmann, Manon L. Schlikker, Maximilian Burmeister, et al.
https://www.science.org/doi/10.1126/sciadv.aef3128

'Only One Conclusion': Radical Study Suggests Life on Earth Arose Twice
Michael Irving
https://www.sciencealert.com/radical-study-suggests-life-on-earth-arose-from-non-living-matter-twice

Wikipedia articles
https://en.wikipedia.org/wiki/Beebe_Hydrothermal_Vent_Field
https://en.wikipedia.org/wiki/Abiogenesis
https://en.wikipedia.org/wiki/Archaea
https://en.wikipedia.org/wiki/Enzyme
https://en.wikipedia.org/wiki/Adenosine_triphosphate
https://en.wikipedia.org/wiki/Tree_of_life_(biology)
https://en.wikipedia.org/wiki/Last_universal_common_ancestor
https://en.wikipedia.org/wiki/Phylogenetic_tree
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Crazy- I'd certainly heard that underwater vents like these may have been an origin point for the earliest life forms, or at least the precursor molecules, but I'd not have thought the deepest known one would give us new info, I'd have thought extremophiles would just be offshoots of other life!

3 weeks ago | Likes 2 Dislikes 0

3 weeks ago | Likes 1 Dislikes 1

Ok, super cool. But what does it mean. My friend is 5 and he needs an explanation.

3 weeks ago | Likes 1 Dislikes 0

"Am Beebe" - Life

3 weeks ago | Likes 3 Dislikes 0

I understood that. Promise

3 weeks ago | Likes 1 Dislikes 0

😊👍

3 weeks ago | Likes 2 Dislikes 0

Who knew Chlamydiae was the origin of life? I’ve been fighting to get rid of it all this time.

3 weeks ago | Likes 1 Dislikes 1

You only have about 50 grams of ATP in your body, but you recycle it a good 1000 times a day.

3 weeks ago | Likes 2 Dislikes 0

Yes. The energy of the ATP molecule is in its phosphate groups.

3 weeks ago | Likes 2 Dislikes 0

I like the title. “Motion of the ocean “

3 weeks ago | Likes 1 Dislikes 1

My dumb ass thought this was 9/11 for a second

3 weeks ago | Likes 4 Dislikes 2

Good show. Bravo.
Now, please apply this level of analysis and expertise to the role of current geoeconomics as an apex predator entity in the ecosystem before it’s too late. As Richard Vevers said in Chasing Coral, we have the knowledge and resources to turn this ship around. Let’s go then. Little else matters at this point.

3 weeks ago | Likes 9 Dislikes 3

I don't think experts in evolutionary biology are going to be of much help on the matter. Should they just stop working on their passions in the meantime?

3 weeks ago | Likes 3 Dislikes 0

I"m not sure I understand. Is the claim that bacteria and archaea came to be separately so there is no LUCA, the last universal common ancestor?

3 weeks ago | Likes 5 Dislikes 0

Not really, just that life evolved away from metabolisms needing metallic catalysts twice, rather than once and then splitting.

3 weeks ago | Likes 3 Dislikes 0

Potentially.

The two branches are kinda assumed to have a common ancestor, but they use entirely-different enzymes for metabolism. For evolution, that’s weird… weird enough that it might not actually be a LUCA, but perhaps different sites with different metal catalysts that started different kinds of biology.

3 weeks ago | Likes 8 Dislikes 0

No. (But it's unclear in this summary, the article gives the details.) They're saying the LUCA came before things counted as "alive."
They assert that to qualify as "life," a thing has to have a self contained metabolism - not relying on metals around them for catalyzing reactions. Since bacteria and archaea use such different enzymes, they conclude that the non-living, pre-cell thing (their LUCA) made the evolutionary jump to self-contained metabolism twice, in two different ways.

3 weeks ago | Likes 5 Dislikes 0

50 kilograms ≈ 110 pounds or 7 stone, 10 pounds

3 weeks ago | Likes 13 Dislikes 2

That is a LOT

3 weeks ago | Likes 2 Dislikes 0

Mitochondria, how do they work?

3 weeks ago | Likes 1 Dislikes 0

Magnets

3 weeks ago | Likes 1 Dislikes 0

So the earth is also just cumming into the ocean?

3 weeks ago | Likes 27 Dislikes 4

Ocean needs cumming

3 weeks ago | Likes 3 Dislikes 1

It has enough in it already with all the whales

3 weeks ago | Likes 3 Dislikes 0

Hey don't kink shame Gaia.

3 weeks ago | Likes 19 Dislikes 0

We’re going to find out that it can do some crazy shit and someone’s going to use it for evil.

3 weeks ago | Likes 3 Dislikes 0

Please don't say it like that

3 weeks ago | Likes 5 Dislikes 0

She's a squirter.

3 weeks ago | Likes 6 Dislikes 1